Alterations in cell adhesion proteins and cardiomyopathy

摘要： Cell adhesive junction is specialized intercellular struc-ture composed of cell adhesion proteins. They are essential to connect adjacent heart muscle cell and make heart contraction effectively and properly. Clini-cal and genetic studies have revealed close relationship between cell adhesive proteins and the occurrence of various cardiomyopathies. Here we will review recent development on the disease phenotype, potential cel-lular and molecular mechanism related to cell adhesion molecules, with particular disease pathogenesis learned from genetic manipulated murine models. ... （共10頁(yè)）